CDH1,CDH2,CDH3,CDH4 anticorps

N° du produit ABIN1679719

Cet anticorps Lapin Monoclonal détecte spécifiquement dans WB et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour CDH1,CDH2,CDH3,CDH4 anticorps (ABIN1679719)

Antigène: CDH1,CDH2,CDH3,CDH4

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human Pan Cadherin

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détail du antigène

Antigène: CDH1,CDH2,CDH3,CDH4

Autre désignation: CDH1/CDH2/CDH3/CDH4

Sujet: This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015],Arc-1, CD324, CDHE, ECAD, LCAM, UVO,Apoptosis,Calcium Signaling,Cancer,CDs,Cell Adhesion,Cell Adhesion_Cadherins,Cell Adhesion_Tight Junctions,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Centrosome,Cytoskeleton,ErbB-HER Signaling Pathway,Immunology & Inflammation,Invasion and Metastasis,Neuroscience,Signal Transduction,Wnt/β-Catenin Signaling Pathway,CDH1/CDH2/CDH3/CDH4

Poids moléculaire: 140 kDa

ID gène: 999, 1000, 1001

UniProt: P12830, P19022, P22223, P33151, P55283, P39038